Defending Barclays Cup champions Zesco United have been against prime promotion contenders from FAZ Division One South Kabwe Warriors in this years quarterfinals.
The two sides will meet in doubleheader clash at Nkoloma Stadium in Lusaka on September 20.
This will be the two sides debut meeting in the Barclays Cup.
Zesco will be chasing an unprecedented fifth Barclays Cup crown while Warriors are searching for their first semifinal appearance in the competition.
In the lunchtime kickoff on the same date, 2010 runners-up Zanaco will face tournament debutants Lumwana Radiants of Division One North.
And 24 hours earlier on September 19 at the same venue, two-time champions Power Dynamos will face Green Buffaloes in the repeat of the 2009 final that the Kitwe side won 2-1.
That quarterfinal clash will be proceeded by Mufulira Wanderers last eight clash against Nkwazi in an all-promotion lunchtime clash.
Wanderers return for a second successive Barclays Cup after making a first round exit at the hands of Zesco last season while Nkwazi are back for the first time since their 2010 quarterfinal appearance.
Winners will advance to the semifinals on October 17 while the final will be played on November 14.
Barclays Cup qualification is determined at the mid-season point with the top six sides in the FAZ Super League and the leaders in Division One North and South making the cut for the eight-team competition.