Zesco United have a second successive date against Guinea opposition in a first round fixture of the CAF Champions League.
Horoya qualified from the preliminary round with a 4-0 home win over AS Douanes of Senegal in Conakry on Sunday to advance by the same aggregate scoreline.
It will be the second time that Zesco will have to go through Guinea opposition after AS Kaloum knocked them out of the second round 5-4 on post match penalties of the 2015 edition of the competition following a 2-2 aggregate result.
Zesco meanwhile advanced to the second round after beating Al Ghazala of South Sudan 1-0 away on February 26 to advance 3-0 on aggregate.
The Ndola club has not played in the group stages since 2009 when it was the first Zambian club to do so under the late Fighton Simukonda.
And Zanaco will travel to Zimbabawe in the first round of the Confederation Cup to face Harare City on March 13.
Harare City beat Adema of Madagascar 3-1 away o advance 6-3 on aggregate.