Nkana on Saturday visit Buildcon at Levy Mwanawasa Stadium seeking to maintain their top four position in the FAZ Super Division.
Kalampa wants to complete a double over Buildcon whom they overcame 1-0 in the first round match played in Wusakile.
Fourth placed Nkana sit on 55 points while Buildcon are 9th on the table with 48 points after 32 matches played.
“We need to take each and every game with a serious approach,” Nkana coach Beston Chambeshi said.
Nkana are searching for their third straight win having beaten Nkwazi 2-0 and Power Dynamos 1-0 in the last two matches.
In other games, Power Dynamos will be searching for their first win in four matches when they host Green Buffaloes at Arthur Davies Stadium.
Second placed Zanaco travel to Godfrey Chitalu Stadium to confront Kabwe Warriors.
Zanaco sit on 60 points, two behind leaders Zesco United, from 32 matches.
Zesco, who have 62 points, will play their match against Nkwazi on Sunday in Lusaka.